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2025), which focus on the comprehensive assessment of all exposures integrating multiple-omics technologies to understand cumulative risks

In addition, ALOXs can directly or indirectly promote lipid oxidation in cell membranes to increase the sensitivity of cells to ferroptosis, especially under the catalysis of ferrous iron [34, 35]

This idea is also supported by Picker and Coyle [113], and has received additional traction through replicated studies demonstrating a transient doubling of SZ risk 2 decades following fetal exposure to famine conditions [114]